Glutamic Acid Decarboxylase Antibody
Autoimmune diseases cause the body to attack itself, which leads to inflammation and results in damage to muscles, tissues, and organs. The inflammation produces antibodies in the blood that can be measured and the levels used to diagnose specific autoimmune diseases. Type I diabetes mellitus (DM) is an autoimmune disease, where the body attacks the pancreatic cells that produce insulin (islet cells). Since high levels of GAD Ab can be measured a number of years before clinical signs of diabetes are seen, this test is a very helpful tool in an attempt to prevent the disease or to better manage the onset, diet and treatment. The test must be done before any insulin therapy is started, since this will cause elevations in these antibodies in the blood. GAD Ab levels are used to diagnose Type I diabetes mellitus (DM), insulin allergy, insulin resistance; or to monitor your condition after a pancreas transplant.
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