Platelet Volume, Mean
Platelets are a blood component made in the bone marrow necessary for normal blood clotting. When injury occurs, platelets will clump (aggregate) at the site, which forms a blood clot and stops the bleeding. Whenever there is an increased need for the bone marrow to produce platelets, there will be an increased number of large immature platelets which increases mean platelet volume. Whenever the bone marrow is unable to produce platelets normally, there will be lower numbers of smaller mature platelets in the blood which decreases mean platelet volume. Measurement of MPV allows your doctor to diagnose the cause of abnormal platelet numbers. Low MPV is seen in people with Wiskott-Aldrich syndrome, bone marrow malfunction due to chemotherapy for cancer, or aplastic anemia. High MPV is seen in people with ITP (idiopathic thrombocytopenia purpura), excessive bleeding due to trauma, leukemia, deficiency of the B vitamins folic acid or vitamin B12, or heart valve disease.
In a medical emergency, step away from this web site and call for emergency help. Remember, we're not doctors and we don't claim to be able to diagnose your condition. The information and services we provide or display here are merely intended to make you a more knowledgeable patient so that you can have smarter conversations with your actual health care providers.